Which of the following clinical features differentiate major neurocognitive disorder from mild neurocognitive disorder? (Select all that apply)

Rationale: C. Inability to perform activities of daily living independently is a hallmark feature of major neurocognitive disorder. Unlike mild neurocognitive disorder, where clients may need only occasional reminders or assistance, major neurocognitive disorder significantly impairs the ability to complete self-care tasks. D. Inability to recognize close family members represents severe cognitive decline affecting memory and recognition, which is typical in advanced stages of major neurocognitive disorder. Mild neurocognitive disorder does not usually involve loss of recognition of familiar people. F. Significant interference with independence in everyday activities is another key differentiator. While mild neurocognitive disorder causes minor difficulties that can be compensated for, major neurocognitive disorder substantially disrupts daily functioning and independence. G. Dependence on round-the-clock supervision reflects the severe functional impairment in major neurocognitive disorder. Clients with mild neurocognitive disorder generally remain independent with minimal supervision. A. Mild impairment that can be compensated with reminders is characteristic of mild neurocognitive disorder, not major. B. Occasional forgetfulness of names is common in normal aging or mild neurocognitive disorder and does not indicate major neurocognitive disorder. E. Gradual decline in memory retrieval occurs in both mild and major neurocognitive disorder, so it does not differentiate the two.