Which of the following considerations are important for a nurse administering morphine and oxybutynin to a client with renal calculi? (Select all that apply)

A. There is no specific requirement to administer morphine before oxybutynin; the order does not affect safety or efficacy. B. Administering both medications in a single dose is not inherently unsafe, though standard dosing guidelines should be followed. C. Oxybutynin is an anticholinergic, which can cause dry mouth, urinary retention, constipation, and blurred vision. Assessing for these side effects is important, particularly in clients with renal calculi who may already have urinary tract issues. D. Morphine is an opioid analgesic and can cause respiratory depression, sedation, and hypotension. Monitoring the client’s respiratory rate, level of consciousness, and oxygen saturation is essential for safety. E. Hyperglycemia is not a common side effect of oxybutynin, so routine monitoring for this is not necessary unless the client has diabetes. F. Adequate hydration is crucial for clients with renal calculi to help prevent further stone formation and assist in flushing existing calculi from the urinary tract.