Which of the following findings by the nurse are considered Major Characteristics of Rheumatic Fever as determined by the Jones Criteria? Select the FIVE that apply.

Rationale: A. Jaundice: This is not part of the Jones Criteria for rheumatic fever. While jaundice may occur with certain liver or hemolytic conditions, it is unrelated to the pathophysiologic features of rheumatic fever. B. Subcutaneous Nodules: These are firm, painless nodules typically found over bony prominences or near joints and are a recognized major criterion for rheumatic fever. They are associated with severe carditis and indicate inflammation of connective tissue. C. Polyarthritis: This is one of the most common major criteria. It involves migratory inflammation affecting large joints, with swelling, redness, and pain that shifts from one joint to another over several days. D. Chorea: Also called Sydenham chorea or “St. Vitus dance,” this involves involuntary, purposeless movements and is a major neurological manifestation of rheumatic fever. It can appear weeks to months after the initial streptococcal infection. E. Carditis: This includes inflammation of the heart’s endocardium, myocardium, and/or pericardium. Carditis is a major criterion and can present with new murmurs, cardiomegaly, or signs of heart failure. F. Erythema Marginatum: This is a distinctive, non-pruritic, pink rash with a clear center and wavy margins that spreads outward. It is one of the major cutaneous manifestations in the Jones Criteria. G. Decreased urine output: This is not part of the Jones Criteria and is more indicative of renal involvement, such as in acute glomerulonephritis, which can occur after streptococcal infections but is a separate condition from rheumatic fever.