Which of the following is a common side effect associated with quinolonest
Explanation & Rationale
A. Nephrotoxicity: Nephrotoxicity is more commonly associated with aminoglycosides and certain chemotherapeutic drugs. While quinolones are excreted by the kidneys, they are not typically linked to significant kidney toxicity as a primary side effect. B. Hypersensitivity reactions: Allergic reactions can occur with any antibiotic, including quinolones, but they are not the hallmark adverse effect. They are less frequent compared to the well-recognized musculoskeletal complications. C. Tendon rupture: Quinolones, such as ciprofloxacin and levofloxacin, are well known for causing tendon inflammation and rupture, particularly the Achilles tendon. This risk is higher in older adults, clients on corticosteroids, and those with kidney disease. D. Ototoxicity: Ototoxicity is associated with aminoglycosides like gentamicin, not quinolones. Hearing loss, tinnitus, or vestibular damage are not common complications of quinolone therapy.