Which of the following is a commonly used approach in substance abuse treatment?

A. Acupuncture: While it may be used as a complementary therapy, it is not a primary approach. B. Prayer: This may provide personal comfort but is not a medical treatment. C. Hypnosis: Hypnosis is not widely used or validated for substance abuse treatment. D. Detoxification: Detoxification is the process of safely removing a substance from the body, often under medical supervision.