Which of the following is a long-acting insulin used to control blood sugar levels?
Explanation & Rationale
Choice A rationale Insulin lispro is a rapid-acting insulin. It is used to cover mealtime blood sugar spikes due to its rapid onset of action, typically within 15 to 30 minutes, and a short duration of action of approximately 3 to 5 hours. Choice B rationale Insulin glargine (Lantus) is a long-acting insulin. It has a slow, sustained absorption and provides a relatively constant basal insulin level over 24 hours with no pronounced peak. This makes it ideal for controlling blood sugar between meals and overnight. Choice C rationale Insulin aspart (Novolog) is another rapid-acting insulin. It is designed to be injected just before or at mealtime to quickly control the rise in blood glucose levels that occurs after eating. Its onset is rapid, and its duration is short. Choice D rationale Regular insulin is a short-acting insulin. It is often used for mealtime coverage, but its slower onset (30 to 60 minutes) and peak (2 to 4 hours) make it less flexible than rapid-acting insulins. It is also used in insulin drips for acute management.