Which of the following is NOT a potential consequence of obesity?
Explanation & Rationale
A. Hypertension: Excess adipose tissue increases vascular resistance and cardiac workload, contributing to elevated blood pressure. Obesity is a well-established risk factor for primary hypertension due to neurohormonal and mechanical mechanisms. B. Stroke: Obesity contributes to atherosclerosis, dyslipidemia, and hypertension, all of which increase the risk of ischemic and hemorrhagic stroke. Vascular inflammation and endothelial dysfunction in obesity further elevate stroke risk. C. Sleep apnea: Obesity, especially central and upper-body adiposity, can narrow the upper airway, increasing the likelihood of obstructive sleep apnea. Fat deposits around the pharynx and reduced chest wall compliance exacerbate airway collapse during sleep. D. COPD: Chronic obstructive pulmonary disease is primarily caused by long-term exposure to inhaled irritants such as tobacco smoke. While obesity can exacerbate breathing difficulties, it is not a direct cause of COPD and therefore is not a typical consequence of obesity. E. Diabetes: Obesity promotes insulin resistance through inflammatory cytokines, adipokines, and lipid accumulation in muscle and liver tissues, making it a major risk factor for type 2 diabetes mellitus.