Which of the following medications is effective for enuresis?

A. Gabapentin is an anticonvulsant and neuropathic pain medication that has no role in treating enuresis. It works by modulating calcium channels and is primarily used for seizures, neuropathic pain, and restless leg syndrome. B. Laxatives. While constipation can contribute to enuresis by exerting pressure on the bladder, laxatives do not directly treat bedwetting. Instead, addressing constipation may help reduce nocturnal enuresis in some cases. C. Desmopressin (DDAVP) is the first-line pharmacologic treatment for enuresis. It is a synthetic analog of antidiuretic hormone (ADH, vasopressin) that reduces night-time urine production, making it effective for nocturnal enuresis (bedwetting) in children. D. SSRIs. Selective serotonin reuptake inhibitors (SSRIs) are used for depression, anxiety, and OCD but have no primary role in enuresis treatment. In some cases, they may actually cause urinary retention or incontinence as a side effect rather than improving enuresis.