Which of the following opioids is most potent?

A. Hydromorphone (Dilaudid): Hydromorphone is approximately 5–7 times more potent than morphine when given orally and even more potent parenterally. Its high affinity for mu-opioid receptors produces stronger analgesic effects at lower doses. B. Morphine: Morphine is the standard reference opioid for potency comparisons. While effective, it is less potent than hydromorphone and requires higher doses to achieve similar analgesia. C. Oxycodone (Roxicodone): Oxycodone is less potent than hydromorphone and slightly more potent than oral morphine. It is effective for moderate to severe pain but does not match hydromorphone in analgesic strength. D. Hydrocodone (Vicodin, Narco): Hydrocodone is a moderate opioid often combined with acetaminophen. It is less potent than morphine, oxycodone, and hydromorphone, making it the least potent.