Which of the following statements is true about a child with Fragile X syndrome?

Choice A reason: Females with Fragile X syndrome typically have milder symptoms than males due to the presence of a second, unaffected X chromosome. Males, having only one X chromosome, are more severely affected. This statement is incorrect and reverses the typical clinical presentation. Choice B reason: Children with Fragile X syndrome generally have a normal life span. While they may experience developmental delays, intellectual disability, and behavioral challenges, the condition does not typically affect life expectancy. Management focuses on supportive therapies and educational interventions. Choice C reason: Joint stiffness is not a hallmark of Fragile X syndrome. In fact, children with Fragile X often have joint hypermobility due to connective tissue abnormalities. Stretching exercises may be used in other conditions but are not a standard intervention for Fragile X. Choice D reason: A small head is not characteristic of Fragile X syndrome. Macrocephaly (larger head size) or normal head size is more typical. Disproportionate small head size may suggest other neurodevelopmental or genetic disorders.