Which of the following symptoms is a common indication of active tuberculosis (TB) infection?

Rationale: A. Acute abdominal pain is not a typical manifestation of pulmonary TB; it may occur with extrapulmonary TB affecting the abdomen, but it is not common. B. Sudden onset of high fever and chills is more characteristic of acute bacterial infections, not the gradual onset of TB. C. Severe headache and neck stiffness suggest meningitis, which could occur with TB meningitis, but this is less common than pulmonary TB. D. Persistent cough lasting more than three weeks is a classic symptom of active pulmonary TB, often accompanied by sputum production, hemoptysis, fatigue, and low-grade fever.