Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.

Choice A rationale: While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function. Choice B rationale: Absorption of oral medications in infants can be unpredictable due to their immature digestive systems. Choice C rationale: Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable. Choice D rationale: Protein binding of drugs is actually less in infants than in adults, not greater.