Which side effect should a client be educated about when prescribed an alpha-glucosidase inhibitor?

A. Suicidal ideations: Alpha-glucosidase inhibitors do not affect central neurotransmitter pathways involved in mood regulation. These agents act locally in the intestine and have no known association with psychiatric adverse effects. B. Angioedema: This reaction involves immunologic or bradykinin-mediated swelling of deep tissues and is typically linked with ACE inhibitors or certain biologics. Alpha-glucosidase inhibitors do not trigger mast-cell–mediated reactions of this type. C. Hyperglycemia: These drugs delay carbohydrate absorption in the small intestine by inhibiting brush-border enzymes, which reduces postprandial glucose spikes. They do not cause hyperglycemia; if anything, they reduce glucose surges following meals. D. Gastrointestinal upset: Alpha-glucosidase inhibitors commonly cause flatulence, abdominal cramping, and diarrhea due to fermentation of undigested carbohydrates in the colon. This GI intolerance results from delayed carbohydrate breakdown and is the primary counseling point for clients.