Nur 315 paediatrics and maternity proctored exam
Which statement is true regarding the genetic transmission of Duchenne muscular dystrophy (DMD)?
Explanation & Rationale
Rationale: A. DMD is caused by mutations in a single gene (DMD gene), not multiple gene expressions. B. DMD is an X-linked recessive disorder, primarily affecting males. Female carriers usually do not show symptoms but can pass the mutated gene to their offspring. C. Autosomal dominant disorders affect males and females equally and only require one mutated gene. DMD does not follow this pattern. D. Carrier states do exist—typically in females—who can pass the defective gene to children without showing full-blown symptoms themselves.
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