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    Pharmacology proctored exam (examplify)

    Which statement represents the advantage of prescribing Ondansetron rather than Promethazine for a client with nausea?

    Explanation & Rationale

    A. Ondansetron can be given earlier and remain effective.: While ondansetron is effective when given before nausea begins, timing of administration is not its primary advantage over promethazine. Both medications can be given prophylactically. B. Ondansetron has minimal adverse effects and Promethazine affects the CNS.: Ondansetron causes fewer sedative and extrapyramidal effects compared to promethazine, which has strong central nervous system depressant properties. This makes ondansetron safer for clients who must remain alert and reduces the risk of confusion or drowsiness. C. Ondansetron is an anti-emetic drug and Promethazine doesn't stop nausea.: Both ondansetron and promethazine are antiemetics, but they act through different mechanisms. Promethazine blocks dopamine and histamine receptors, effectively reducing nausea. D. Ondansetron is a newer medication and more available.: Although ondansetron is newer, medication choice should be based on efficacy and safety rather than novelty or availability. The major advantage of ondansetron lies in its superior safety profile and minimal CNS depression.

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