Which statements are true about bupropion? (Select all that apply)

Choice A reason: Bupropion is not primarily a sedative; it is an atypical antidepressant that stimulates norepinephrine and dopamine. It may cause insomnia, not promote sleep, making this statement incorrect. Sedative medications like zolpidem are used for sleep, not bupropion, which has activating properties. Choice B reason: Bupropion has a lower risk of sexual dysfunction compared to SSRIs, making it a suitable alternative for depression treatment in patients experiencing this side effect. Its mechanism avoids serotonin-related sexual issues, supporting its use in such cases, making this a correct choice. Choice C reason: Bupropion is FDA-approved for major depressive disorder, acting on norepinephrine and dopamine to alleviate depressive symptoms. It is commonly prescribed for depression, making this statement true and a correct choice, as it aligns with its primary clinical use. Choice D reason: Bupropion, under the brand Zyban, is approved for smoking cessation, as it reduces nicotine cravings and withdrawal symptoms by modulating dopamine pathways. This evidence-based use makes the statement true, correctly identifying bupropion’s role in smoking cessation programs.