Which two types of lesions are characterized as vesicles? (Select all that apply.) Multiple options may be correct
Explanation & Rationale
A. Herpes zoster: Herpes zoster, also known as shingles, is caused by reactivation of the varicella-zoster virus. It presents as clusters of small, fluid-filled vesicles on an erythematous base along a dermatomal distribution. The vesicles contain clear fluid and are a hallmark feature of this viral infection, often accompanied by pain, tingling, or burning sensations. B. Varicella: Varicella, or chickenpox, is a primary infection with the varicella-zoster virus and presents with widespread vesicular lesions. These lesions typically begin as macules, progress to papules, and then develop into vesicles filled with clear fluid. Vesicles eventually crust over as part of the natural course of the disease, reflecting active viral replication in the skin. C. Psoriasis: Psoriasis is a chronic autoimmune skin condition characterized by erythematous plaques with silvery scales. It does not produce vesicles; instead, the lesions are thickened, raised, and scaly. Vesicular formation is not a typical feature of psoriasis. D. Warts: Warts are caused by human papillomavirus (HPV) and present as firm, hyperkeratotic papules or nodules. They are solid lesions without fluid-filled vesicles and are distinct from vesicular lesions. E. Insect bites: Insect bites typically cause localized erythema, swelling, and sometimes small papules or wheals. They may blister occasionally, but the lesions are generally not true vesicles filled with fluid in a consistent pattern, unlike viral vesicular eruptions.