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    Nur 301 pharmacology proctored exam (examplify)

    Which would the nurse be prepared to administer to a client who has overdosed on diphenoxylate with atropine?

    Explanation & Rationale

    A. Naloxone: Diphenoxylate is an opioid derivative used to treat diarrhea, and naloxone is an opioid antagonist that reverses its central nervous system and respiratory depressant effects in overdose. It is the drug of choice in this situation. B. Flumazenil: Flumazenil is a benzodiazepine antagonist used to reverse the effects of drugs like diazepam or lorazepam. It has no therapeutic effect on opioid toxicity and would not be useful here. C. Digibind: Digibind is an antidote used specifically for digoxin toxicity. It binds to circulating digoxin to neutralize its effects, but it has no role in opioid-related overdoses. D. Glucagon: Glucagon is used in cases of beta-blocker overdose or severe hypoglycemia. It is not effective against diphenoxylate toxicity and would not be administered in this context.

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