You are caring for a client with hyperthyroidism that is taking propylthiouracil (PTU). The client reports that she misunderstood the instructions and took more doses than her prescribed dosage. The client also reported drowsiness, weight gain, edema, and cold intolerance. You suspect which of the following adverse effects of this drug?

A. "I will take both aluminum hydroxide (Amphojel) and cimetidine (Tagamet HB) at the same time." – This is correct. Taking aluminum hydroxide and cimetidine simultaneously reduces the effectiveness of cimetidine by impairing its absorption. This statement indicates a need for further teaching. B. "I will take aluminum hydroxide (Amphojel) 1 hour before taking cimetidine (Tagamet HB)." – This is incorrect. Taking aluminum hydroxide 1 hour before cimetidine allows enough time for the antacid's effects on stomach acidity to stabilize, reducing interference. C. "I can take aluminum hydroxide (Amphojel) 2 hours before taking cimetidine (Tagamet HB)." – This is incorrect. Taking the antacid 2 hours before cimetidine provides sufficient time for proper absorption of the medication. D. None of the above – This is incorrect because statement A reflects improper administration.