You are preparing a presentation on arthritis. You know the differences between osteoarthritis (OA) and rheumatoid arthritis (RA) include that: (Select all that apply.)

A. OA is a localized process, whereas RA may be systemic: Osteoarthritis is a degenerative joint disease limited to affected joints. Rheumatoid arthritis is an autoimmune condition that affects multiple joints and can cause systemic inflammation involving organs such as the lungs and heart. B. Initial treatment of both OA and RA is usually nonpharmacological using heat or exercise: Both conditions benefit from conservative management approaches such as physical therapy, range-of-motion exercises, weight management, and the application of heat to relieve stiffness. C. Both OA and RA have an acute onset in older adults: Neither OA nor RA typically presents acutely. OA develops gradually over years due to wear and tear, while RA progresses over weeks to months with joint pain and swelling. D. OA usually impacts distal interphalangeal joints; RA impacts proximal interphalangeal joints: Osteoarthritis commonly affects weight-bearing joints and distal finger joints (Heberden’s nodes), whereas rheumatoid arthritis primarily involves proximal interphalangeal and metacarpophalangeal joints, leading to symmetrical pain and deformity.