You are the APN (Advanced Practice Nurse) and you are prescribing Buspirone Buspar) to your patient. What key information should be shared with the patient when prescribing that?

A. Do not take with grapefruit juice: Grapefruit juice can inhibit the CYP3A4 enzyme in the liver, which metabolizes buspirone. This interaction increases the drug’s plasma concentration, raising the risk of excessive sedation, dizziness, or other adverse effects. Patients should be counseled to avoid grapefruit and related products. B. You do not need to take this med with a full 8-ounce glass of water: While adequate hydration is generally recommended, there is no requirement for a full 8-ounce glass specifically with buspirone. This instruction is not clinically significant for efficacy or safety. C. Sit upright for 60 minutes after taking: Buspirone does not pose a risk for esophageal irritation or require prolonged upright positioning, unlike certain medications such as bisphosphonates. This instruction is unnecessary. D. Report palpitations to your provider: Palpitations are not a common or major adverse effect of buspirone. While patients should report any unusual cardiac symptoms, counseling should focus on more likely drug interactions and side effects, such as dizziness or sedation.